Acne and Retinoids
One of the most common ways of treating acne is the use of retinoids. Retinoids are substances derived from Vitamin A, which attempt to cure acne by normalizing the lifecycle of follicle cells. There are two types of such substances, based on application: external (topical) and oral. The best known external retinoids are Retin-A, Differin and Tazorac, while the oral retinoids list is headed by the popular Accutane.
“The biggest drawback of retinoids is the long list of side effects, which sometimes makes retinoids look like a disease rather than a cure.”
Retinoids are derivatives of Vitamin A and share the parent substance’s effects of reducing the secretion of oil from the glands located in the skin. This primary effect is what makes retinoids so effective against acne. The long-term (4-6 months) decrease in oil secretion means that hair follicles are less likely to clog and turn into pimples and, in most cases, acne is gone for good by the end of the treatment period. However, about one quarter of the patients who used Accutane or other drugs based on isotretinoin may relapse and require additional treatment.
Side Effects of Retinoids
But the biggest drawback of retinoids is the long list of side effects, which sometimes makes retinoids look like a disease rather than a cure. Retinoids are used only under the close supervision of a dermatologist precisely because of these side effects. If a patient needs more than one treatment, the doctor will always insist on letting a few months pass between the treatments in order to give the body a chance to recover. The most common side effects are dry skin and nosebleeds. Many patients have also reported liver problems, while a few complained of depression.
However, the scientific community is still split on the issue of depression. More seriously, isotretinoin is known to cause birth defects, which is why female patients have to use two separate forms of birth control or vow abstinence during the treatment. Pregnant women are not allowed to use anything but the mildest treatments.
The bottom line is that retinoids are a good idea if one can cope with the side effects. This begs the question: why not use something just as effective, but without the side effects. Acne treatment systems, such as ClearPores, are also popular because of their success in dealing with the condition, but lack the extreme side that makes retinoids a pain to use. The choice between these treatments is yours.
Related acne information:
What causes Acne - the development and cause of acne.
Self Help - explaining strategies to help prevent pimples.
Syndicated by ClearPores™ skin cleansing system and the ClearPores information center.
Glossary of terms found on this page:
Retinoids: the Retinoids are a class of chemical compounds that are related chemically to vitamin A. Retinoids are used in medicine, primarily due to the way they regulate epithelial cell growth. Retin-A: a trademarked brand name for Tretinoin, a retinoic acid cream used to treat acne and keratosis pilaris; it is claimed that it stimulates skin cell turnover and smoothes wrinkles. A derivative of vitamin A, which is required for proper bone development, night vision, and skin integrity. It is used by some as a hair loss treatment. Differin: a prescription drug related to vitamin A; used to treat acne and other skin disorders. Tazorac: (tazarotene) Cream and Gel 0.1% are an effective acne treatment medicine for adult and teen acne. Accutane: Isotretinoin is a medication used for the treatment of acne. It is a retinoid, meaning it is derived from Vitamin A and is found naturally in the body, produced by the liver in small quantities. Isotretinoin is sold under many brand names, including Accutane® and Roaccutane® by Roche. Hair Follicles: A hair follicle is part of the skin that grows hair by packing old cells together. Inside the follicle the sebaceous gland is found, a tiny oil-producing gland found everywhere except on the palms and soles of the feet. The thicker density of hair, the more sebaceous glands are found. Isotretinoin: A drug that belongs to the family of drugs called retinoids. It is used in the treatment of acne and psoriasis and is being studied in cancer prevention. Also called 13-cis retinoic acid.